Principal Scientist, Peptide Protein Chemistry
Company: RPM Research
Location: San Diego
Posted on: April 20, 2024
Job Description:
Principal Scientist, Peptide Protein Chemistry Apply Type Direct
Hire ID BN38-2731702 Posted Jan 25, 2024 Principal Scientist,
Peptide Protein Chemistry This BioPharma is a neuroscience-focused,
biopharmaceutical company with a simple purpose: to relieve
suffering for people with great needs, but few options. We are
dedicated to discovering and developing life-changing treatments
for patients with under-addressed neurological, endocrine and
psychiatric disorders. The company's diverse portfolio includes
FDA-approved treatments for tardive dyskinesia, Parkinson's
disease, endometriosis* and uterine fibroids*, as well as clinical
programs in multiple therapeutic areas. For three decades, we have
applied our unique insight into neuroscience and the
interconnections between brain and body systems to treat complex
conditions. We relentlessly pursue medicines to ease the burden of
debilitating diseases and disorders, because you deserve brave
science. *in collaboration with AbbVie About the Role: Seeking a
highly motivated and talented peptide chemistry leader to join our
new discovery peptide research group. The successful candidate will
work on the design, synthesis and characterization of novel
peptides and peptide conjugates to discover next-generation
peptide-based therapeutics. Your expert synthetic knowledge and
proven design and synthetic accomplishments will enable you to have
significant impact on Company's projects. This is an exciting
opportunity to grow your career and help discover peptide
therapeutics of the future. _ Your Contributions (include, but are
not limited to):
- Lead projects and teams towards agreed upon goals, ultimately
working towards clinical candidate peptide nomination
- Design, synthesize and characterize peptides, small proteins
and chemically-modified analogs using state-of-the-art synthesis,
bioconjugation, purification, analytical and biophysical
techniques
- Independent data-driven optimization of peptide SAR
- Effective communication of scientific rationale, results and
interpretation at project, team and departmental meetings,
contributing to strategic discussions.
- Active collaboration and sharing of expertise with
colleagues
- Builds and enhances internal and external professional
relationships
- Aid in recruiting of peptide group scientists
- Future management of more junior scientists Requirements: - PhD
in organic chemistry, or related field, with at least 5 subsequent
years of experience in an industrial setting - Proficient in all
aspects of modern peptide synthesis, protein bioconjugation,
peptide and protein purification and analysis - Experience in
optimizing and delivering peptide-protein conjugates as candidates
for clinical trial - Strong publication record of accomplishment -
Strong understanding of peptide and protein structure and
associated biophysical techniques to assess structure, stability
and behavior in solution - Experience in bioconjugation,
time-extension and formulation strategies for peptides and proteins
- Motivated to maintain a strong laboratory presence along with
design and planning activities - Excellent interpersonal skills
with strong oral and written communication abilities -
Demonstration of cross-functional understanding related to drug
development - Assimilates data and research findings outside of our
co. for application to new scientific projects - Advanced knowledge
and demonstrated ability working with / recommending a variety of
laboratory equipment/tools - Prioritizes teamwork above all else -
Exhibits leadership skill and ability, typically leads lower levels
and/or indirect teams - Excellent computer, communications,
problem-solving, and analytical thinking skills - Sees broader
picture, impact on multiple programs, teams and/or departments -
Ability to meet multiple deadlines across a variety of
projects/programs, with a high degree of accuracy and efficiency
position is located in San Diego, CA and includes competitive base
salary, bonus, full benefits and a full relocation (robust
relocation package including help with real estate, temporary
housing and extra financial bonus)
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Keywords: RPM Research, Santee , Principal Scientist, Peptide Protein Chemistry, Other , San Diego, California
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